0218: Influence of gender on the distribution of anatomic anomalies of the pulmonary veins (PVs) in a cohort of 38 patients with atrial fibrillation (AF)

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• 作者：Lobna Laroussi ; ^{lobna_laroussi@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Afef Ben Halima ; Emna Bouzgarrou ; Zied Ibn El Haj ; Haytham Raddaoui ; Ahmed Houmed ; Faouzi Addad ; Asma Zidi ; Salem Kachboura
• 刊名：Archives of Cardiovascular Diseases Supplements
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：8
• 期：1
• 页码：69
• 全文大小：50 K

文摘

Obstructive sleep apnea (OSA) is associated with oxidative stress, risk factors including hypertension, and with binary presence of coronary artery disease (CAD). However, whether OSA contributes to the severity of CAD and to future adverse events in patients with CAD remains unknown.

Aim

The aim of this study was to investigate the association between severe OSA and multivessel CAD.

Methods

We examined the apnea hypopnea index (AHI) using polygraphy (PG) in 60 consecutive patients with ACS who underwent coronary angiography. OSA was defined by AHI≥5 events per hour and was considered severe if the AHI≥30 events per hour. The Friesinger score was calculated for each patient from the coronary angiography to evaluate the severity of CAD.

Results

The average age of patients was 59.73 years±10.1 years. The sex ratio was 1, 5.

61, 7% of patients had an AHI≥5 and 21,7% had severe OSA with AHI≥30. The Friesinger score was significantly greater in the group with multivessel CAD (11, 28±4, 17 versus 5, 35±3, 96, p=0,0001). There were no differences between patients having multivessel CAD and those with single-vessel CAD regarding clinical characteristics.

Table summarizes these results.