Photosensitized rose Bengal-induced phototoxicity on human melanoma cell line under natural sunlight exposure
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- 作者：Ajeet K. Srivastava ; 1 ; Syed Faiz Mujtabaa ; 1 ; Ashish Dwivedia ; Saroj K. Amara ; c ; Shruti Goyala ; c ; Ankit Vermaa ; Hari N. Kushwahaa ; Rajnish K. Chaturvedib ; c ; Ratan Singh Raya ; c ; rsray@iitr.res.in" class="auth_mail" title="E-mail the corresponding author
- 关键词：Rose Bengal ; Melanoma cells ; Singlet oxygen ; DNA damage ; Apoptosis
- 刊名：Journal of Photochemistry and Photobiology B: Biology
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：156
- 期：Complete
- 页码：87-99
- 全文大小：4756 K
文摘
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Photomodification of rose Bengal under natural sunlight exposure.
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Phototoxicity of rose Bengal through type-II photodynamic reaction by generating 1O2.
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Role of DNA damage and lipid peroxidation in rose Bengal phototoxicity.
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Photosensitized rose Bengal induced apoptotic cell death.
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Up-regulation of p53 and bax gene expression.