Colostrum proinflammatory cytokines as biomarkers of bovine immune response to bovine tuberculosis (bTB)

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• 作者：Eduardo Sá ; nchez-Soto^a ; Rosa Ponce-Ramos^a ; Rodolfo Herná ; ndez-Gutié ; rrez^a ; ^{rhgutierrez@ciatej.mx} ; Abel Gutié ; rrez-Ortega^a ; ^{aortega@ciatej.mx} ; Angel H. Á ; lvarez^a ; ^{aalvarez@ciatej.mx} ; Moisé ; s Mart&iacute ; nez-Velá ; zquez^a ; Angel E. Absaló ; n^b ; ^{aabsalon@ipn.mx} ; Pablo Ortiz-Lazareno^c ; ^{pablolazareno@gmail.com} ; Alberto Limó ; n-Flores^d ; ^{aylf10@hotmail.com} ; Ciro Estrada-Chá ; vez^a ; ^{cestrada.ciatej@gmail.com} ; Sara E. Herrera-Rodr&iacute ; guez^a ; ^{sherrera@ciatej.mx}
• 关键词：Gamma interferon (IFN-γ) ; Colostrum mononuclear cells (CMC) ; Tuberculin reactors (TST+) ; Tuberculin non-reactors (TST&minus ; ) ; BOVIGAM responder (Bov+) ; BOVIGAM non-responders (Bov&minus ; )
• 刊名：Microbial Pathogenesis
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：103
• 期：Complete
• 页码：57-64
• 全文大小：783 K
• 卷排序：103

文摘

Cytokines presented in this work, have the potential to be used as diagnosis of bTB in bovine colostrum. IL-1-α and TNF-α in colostrum have a suitable mean to identify reactors and non-reactor cattle to bTB. Current diagnostic screening can be improve by IL-1-α and TNF-α, and can be implemented in dairy herds.