Recombinantly produced banana lectin isoform promotes balanced pro-inflammatory response in the colon
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- 作者：Emilija Marinkovića ; Ivana Lukića ; Dejana Kosanovića ; Aleksandra Inić-Kanadaa ; 1 ; Marija Gavrović-Jankulovićb ; Marijana Stojanovića ; mstojanovic@torlak.rs" class="auth_mail" title="E-mail the corresponding author
- 关键词：Banana lectin ; Colon ; Immunostimulation
- 刊名：Journal of Functional Foods
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：20
- 期：Complete
- 页码：68-78
- 全文大小：1272 K
文摘
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The influence of rBanLec on the immune response in the colon of mice was evaluated.
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Three different concentrations of rBanLec were administered.
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Skew of local immune response towards Th1/Th17 depended on applied rBanLec concentration.
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In all cases pro-inflammatory immune response was counterbalanced by IL-10.
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rBanLec transitionally augmented MPO activity and enhanced NO production.