The synthesis of 3-sulfenylflavones via FeCl₃-promoted regioselective cyclization of alkynyl aryl ketones with N-arylthiobenzamides

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• 作者：Lin-Feng Shi ; Xing-Guo Zhang ; Xiao-Hong Zhang ; ^{kamenzxh@wzu.edu.cn}
• 关键词：FeCl3-promoted ; Cyclization ; N-arylthiobenzamides ; 3-sulfenylflavones
• 刊名：Tetrahedron
• 出版年：2016
• 出版时间：29 December 2016
• 年：2016
• 卷：72
• 期：52
• 页码：8617-8622
• 全文大小：696 K
• 卷排序：72

文摘

A FeCl3-promoted regioselective cyclization of alkynyl aryl ketones with N-arylthiobenzamides had been developed for the synthesis of 3-sulfenylflavones derivatives. Various alkynyl aryl ketones and N-arylthiobenzamides with a number of functional groups were compatible in this reaction to afford the corresponding 3-sulfenylflavones in moderate to good yields. The mechanism was described in detail.