D-allose protects the blood brain barrier through PPARγ-mediated anti-inflammatory pathway in the mice model of ischemia reperfusion injury

详细信息    查看全文

• 作者：Tao Huang ; Dakuan Gao ; Yue Hei ; Xin Zhang ; Xiaoyan Chen ; Zhou Fei ; ^{zhoufeishaanxi@163.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：BBB Permeability ; D-Allose ; IR Injury ; PPARγ ; TNF-α
• 刊名：Brain Research
• 出版年：2016
• 出版时间：1 July 2016
• 年：2016
• 卷：1642
• 期：Complete
• 页码：478-486
• 全文大小：7632 K

文摘

<dl class="listitem" id="list_li0005"><dt class="label">•dt><dd>

d="p0005">D-allose-2 inhibited cell apoptosis in the mice MCAO/Rep model.

dd><dt class="label">•dt><dd>

d="p0010">D-allose-2 attenuated BBB permeability in the mice MCAO/Rep model.

dd><dt class="label">•dt><dd>

d="p0015">D-allose-2 inhibited the inflammatory cytokines levels in the mice MCAO/Rep model.

dd><dt class="label">•dt><dd>

d="p0020">D-allose weakened the inflammation-related molecules in the mice MCAO/Rep model.

dd><dt class="label">•dt><dd>

d="p0025">D-allose-2 suppressed the inflammation via PPARγ-dependent pathway after MCAO/Rep.

dd>dl>