Chronic intermittent ethanol exposure during adolescence: Effects on stress-induced social alterations and social drinking in adulthood
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- 作者：Elena I. Varlinskaya ; varlinsk@binghamton.edu ; Esther U. Kim ; Linda P. Spear
- 关键词：Adolescence ; Ethanol ; Anxiety ; Stress ; Social facilitation ; Sex differences ; Anhedonia
- 刊名：Brain Research
- 出版年：2017
- 出版时间：1 January 2017
- 年：2017
- 卷：1654
- 期：part_PB
- 页码：145-156
- 全文大小：602 K
- 卷排序：1654
文摘
Early adolescent ethanol exposure (AIE) produced social anxiety in males only. Repeated restraint had social impairing effects in both males and females. AIE curbed sensitivity to the social impairing effects of repeated restraint. AIE eliminated corticosterone habituation to repeated restraint in both sexes. The combination of AIE and stress induced anhedonia only in males.