Mixing test specific cut-off is more sensitive at detecting lupus anticoagulants than index of circulating anticoagulant
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- 作者：Gary W. Moorea ; gary.moore@viapath.co.uk" class="auth_mail" title="E-mail the corresponding author ; Aidan P. Culhanea ; Christopher R. Dawa ; Charlotte P. Noronhaa ; Osamu Kumanob
- 关键词：aβ2GPI ; anti-β2-glycoprotein I antibodies ; aCL ; anticardiolipin antibodies ; aPL ; antiphospholipid antibodies ; APS ; antiphospholipid syndrome ; APTT ; activated partial thromboplastin time ; dAPTT ; dilute activated partial thromboplastin time ; DOAC ; direct oral anticoagulant ; dRVVT ; dilute Russell's viper venom time ; ICA ; index of circulating anticoagulant ; LA ; lupus anticoagulant(s) ; MTC ; mixing test-specific cut-off ; NPP ; normal pooled plasma ; PPP ; platelet poor plasma ; PT ; prothrombin time ; RI ; r
- 刊名：Thrombosis Research
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：139
- 期：Complete
- 页码：98-101
- 全文大小：235 K
文摘
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Interpreting LA mixing tests with MTC detects more LA than ICA.
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Some LA can be detected without mixing tests.
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LA manifestation in mixing tests appears to be a function of more than just potency.