Treatment of chronic hepatitis D with interferon alpha-2b in patients with human immunodeficiency virus infection

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• 作者：Puoti ; Massimo ; Rossi ; Stefania ; Forleo ; Maria Antonia ; Zaltron ; Serena ; Spinetti ; Angiola ; et. al.
• 关键词：HBV ; HCV ; HDV ; Hepatitis ; HIV ; Interferon.
• 刊名：Journal of Hepatology
• 出版年：1998
• 出版时间：July, 1998
• 年：1998
• 卷：29
• 期：1
• 页码：45-52
• 全文大小：114 K

文摘

Background/Aims: Hepatitis delta virus (HDV) coinfection is frequent in patients infected with human immunodeficiency virus (HIV), and it may cause death independently of the development of full-blown AIDS. In order to evaluate the efficacy and tolerability of interferon alpha in the treatment of hepatitis delta in HIV-infected patients, and to compare them with those observed in anti-HIV-seronegative patients,we carried out an open uncontrolled trial on 21 HIV-uninfected and 16 HIV-infected patients without severe immunodeficiency.