One-day versus two-day cleansing for colon capsule endoscopy: a prospective randomized pilot study

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• 作者：Laura Ramos^a ; Onofre Alarcó ; n^a ; Zaida Adrian^a ; Antonio Z. Gimeno-Garc&iacute ; a^a ; David Nicolá ; s-Pé ; rez^a ; Alejandro Jimé ; nez-Sosa^b ; Enrique Quintero^a ; ^{equinter@gmail.com" class="auth_mail}
• 关键词：CCE ; colon capsule endoscopy ; PEG ; polyethylene glycol ; NaP ; sodium phosphate ; CC ; conventional colonoscopy
• 刊名：Gastroenterolog铆a y Hepatolog铆a
• 出版年：March, 2014
• 年：2014
• 卷：37
• 期：3
• 页码：101-106
• 全文大小：248 K

文摘

Background

Standard bowel cleansing for colon capsule endoscopy (CCE) requires a liquid diet and bowel laxatives for at least 2 days, which is a major drawback of this procedure and affects tolerance and acceptability.

Objective

To compare the quality of colon cleanliness achieved with one-day versus two-day bowel preparation in outpatients undergoing CCE.

Methods

Patients were randomly assigned to one of two groups: group I (one-day schedule, n = 20) received a fiber-free diet and 3 L of polyethylene glycol (PEG) on day 0; group II (two-day schedule, n = 20) received a liquid diet and 3 L of PEG in the evening of day 鈭?, and 1 L of PEG in the early morning of day 0. In both groups, the patients received 15 mg bisacodyl on day 鈭? and one or two additional sodium phosphate (NaP) boosters following capsule ingestion. Each colon segment was assessed for cleanliness using a four-point grading scale (excellent = 1, good = 2, fair = 3, and poor = 4). For the final analysis, colon cleanliness was rated as adequate (good or excellent) or inadequate (fair or poor).

Results

Overall colon cleanliness was adequate in 94% (CI 91-97) of patients in group I versus 80% (CI 72-88) in group II (P = 0.27). No significant differences were observed in the per-segment quality of colon cleansing between the two groups. CCE reached the rectum in 80% (CI 73-87) of patients in group I versus 75% (CI 67-83) in group II (p = 0.59).

Conclusion

The quality of colon cleanliness achieved with one-day bowel preparation is equivalent to that of the standard two-day schedule in patients undergoing CCE.