Associations between the CNTNAP2 gene, dorsolateral prefrontal cortex, and cognitive performance on the Stroop task

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• 作者：Bi Zhu^a ; ^b ; ^c ; ^{zhubi@bnu.edu.cn} ; Chuansheng Chen^d ; Gui Xue^a ; ^b ; Xuemei Lei^e ; Yunxin Wang^f ; Jin Li^g ; Robert K. Moyzis^h ; Jun Li^a ; ^b ; Qi Dong^a ; ^b ; Chongde Lin^a ; ^b ; ^c
• 关键词：DLPFC ; dorsolateral prefrontal cortex ; ICV ; intracranial volume ; LD ; linkage disequilibrium ; RT ; reaction time ; SNPs ; single nucleotide polymorphisms
• 刊名：Neuroscience
• 出版年：2017
• 出版时间：20 February 2017
• 年：2017
• 卷：343
• 期：Complete
• 页码：21-29
• 全文大小：957 K
• 卷排序：343

文摘

The CNTNAP2 genetic variations were associated with DLPFC volume and surface area. Subjects with greater left DLPFC surface area had better cognitive performance. Left DLPFC surface area mediated the association between CNTNAP2 and cognition.