Developmental Control of Cell-Cycle Compensation Provides a Switch for Patterned Mitosis at the Onset of Chordate Neurulation
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- 作者：Yosuke Ogura1 ; 2 ; ogura@cdb.riken.jp" class="auth_mail" title="E-mail the corresponding author ; Yasunori Sasakura1
- 刊名：Developmental Cell
- 出版年：2016
- 出版时间：18 April 2016
- 年：2016
- 卷：37
- 期：2
- 页码：148-161
- 全文大小：7094 K
文摘
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The mitotic wave occurring during ascidian neurulation reflects S-phase asynchrony
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S-phase asynchrony is offset by compensatory asynchronous G2 phase until neurulation
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Mitotic timing controlled by a compensatory G2 phase is critical for morphogenesis
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Differential cdc25 expression, regulated by GATA and AP-2, governs G2-phase length