Aging: Treating the Older Patient

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• 作者：Ashley Rosko¹ ; ^&dagger ; ; Andrew Artz² ; ^&Dagger ; ; ^{aartz@medicine.bsd.uchicago.edu}
• 关键词：Multiple myeloma ; Acute myeloid leukemia ; Transplant ; Elderly ; Geriatric assessment ; Autologous ; Allogeneic
• 刊名：Biology of Blood and Marrow Transplantation
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：23
• 期：2
• 页码：193-200
• 全文大小：470 K
• 卷排序：23

文摘

Despite the greater use of autologous transplant for multiple myeloma and allogeneic transplant for AML, significant underuse persists. A geriatric assessment is a multidimensional tool to assess physiologic reserve and can be used to assess fitness for transplant. Aging biomarkers paired with geriatric metrics may be a novel method to assess frailty and gauge risk of treatment toxicity in the future. Hematopoietic cell transplant outcomes can achieve favorable disease-free survival rate in older adults both in myeloma and AML.