Stress-induced change in serum BDNF is related to quantitative family history of alcohol use disorder and age at first alcohol use

详细信息    查看全文

• 作者：Shobhit Sharma^a ; Reiko Graham^b ; Rodney Rohde^c ; Natalie A. Ceballos^b ; ^{nc18@txstate.edu}
• 关键词：Alcohol ; BDNF ; Stress ; Age at first alcohol use ; BDNF Val66Met polymorphism (rs6265) ; Family history of alcohol use disorder
• 刊名：Pharmacology Biochemistry and Behavior
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：153
• 期：Complete
• 页码：12-17
• 全文大小：379 K
• 卷排序：153

文摘

Acute stress reduced serum BDNF levels in healthy social drinkers. Family history and age at first drink accounted for 15% of the variance in ΔBDNF. BDNF stress-reactivity is influenced by both heritable and environmental factors.