Association of elevated rotavirus-specific antibody titers with HBGA secretor status in Swedish individuals: The FUT2 gene as a putative susceptibility determinant for infection
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- 作者：Gö ; kç ; e Gü ; naydına ; 1 ; Johan Nordgrenb ; 1 ; Sumit Sharmab ; Lennart Hammarströ ; ma ; lennart.hammarstrom@ki.se" class="auth_mail" title="E-mail the corresponding author
- 关键词：HBGA ; histo-blood group antigen ; IgAD ; IgA-deficiency ; SWC ; Swedish healthy blood donors ; Se ; secretor ; Le ; Lewis
- 刊名：Virus Research
- 出版年：2016
- 出版时间：4 January 2016
- 年：2016
- 卷：211
- 期：Complete
- 页码：64-68
- 全文大小：729 K
文摘
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We examined changes in rotavirus specific antibody titers in individuals with different FUT2/FUT3 SNPs.
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Secretors show elevated serum specific IgGs.
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Neutralizing antibody titers to the Wa strain were significantly higher in secretors.
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Neutralizing antibody titers to the ST3 strain were similar in all individuals.