Novel magnetic nanoparticles Fe₃O₄-immobilized domino Knoevenagel condensation, Michael addition, and cyclization catalyst

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• 作者：Amin Rostami ; ^{a_rostami372@yahoo.com} ; Bahareh Atashkar ; Hoshyar Gholami
• 关键词：Magnetic nanoparticles ; Guanidine ; Basic nanocatalyst ; Knoevenagel condensation ; Chromene derivatives
• 刊名：Catalysis Communications
• 出版年：2013
• 出版时间：5 July, 2013
• 年：2013
• 卷：37
• 期：Complete
• 页码：69-74
• 全文大小：2198 K

文摘

The synthesis, characterization and applications of guanidine supported on magnetic nanoparticles Fe₃O₄ (MNPs-Guanidine) as a novel magnetically separable base nanocatalyst are described. We have studied the application of this new catalyst for the Knoevenagel condensation reaction of aromatic aldehydes with malononitrile or cyanoacetate in PEG/water = 1:1 at room temperature. Also, the three-component and one-pot synthesis of 2-amino-4H-chromenes and 2-amino-4H-benzo[h]chromenes by condensing aldehydes, malononitrile and cyclic 1,3-dicarbonyl/¦Á-naphthol, in the presence of catalytic amount of MNPs-Guanidine under same conditions is investigated. The supported catalyst could simply be separated and recovered from the reaction mixture with the assistance of an external magnet and reused several times.