The Role of 尾 Cell Glucagon-like Peptide-1 Signaling in Glucose Regulation and Response to Diabetes Drugs
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- 作者：Eric P. Smith1 ; Zhibo An1 ; Constance Wagner1 ; Alfor G. Lewis1 ; Eric B. Cohen1 ; Bailing Li1 ; Parinaz Mahbod1 ; Darleen Sandoval1 ; Diego Perez-Tilve1 ; Natalia Tamarina3 ; Louis H. Philipson3 ; Doris A. Stoffers4 ; Randy J. Seeley1 ; David A. D&rsquo ; Alessio1 ; 2 ; dalessd@ucmail.uc.edu" class="auth_mail
- 刊名：Cell Metabolism
- 出版年：3 June 2014
- 年：2014
- 卷：19
- 期：6
- 页码：1050-1057
- 全文大小：1991 K
文摘
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尾 cell Glp1rs are not necessary for normal oral glucose tolerance in lean mice
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The incretin effect of GLP-1 is not mediated through an endocrine mechanism
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尾 cell Glp1rs are required for normal responses to hyperglycemia and GLP1R agonists
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DPP-4 inhibitors improve glucose tolerance through non-尾 cell Glp1r