Application of polyhydroxylated fullerene derivatives in hemoglobin biosensors with enhanced antioxidant capacity

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• 作者：Xihong Guo ; Shangyuan Yang ; Rongli Cui ; Jian Hao ; Hong Zhang ; Jinquan Dong ; Baoyun Sun ; ^{sunby@ihep.ac.cn}
• 关键词：Electrochemical biosensors ; Hemoglobin ; Fullerene derivatives ; Antioxidant ; H2O2
• 刊名：Electrochemistry Communications
• 出版年：2012
• 出版时间：July, 2012
• 年：2012
• 卷：20
• 期：Complete
• 页码：44-47
• 全文大小：371 K

文摘

Hemoglobin (Hb) biosensors based on polyhydroxylated fullerene derivatives were constructed through layer-by-layer assembly. Not only could fullerene derivatives provide a favorable microenvironment to realize the direct electrochemistry and electrocatalysis of Hb, but they could reduce the oxidant damage for Hb caused by the attack of H₂O₂ as well. Moreover, the antioxidant effect was closely related with fullerene species.