Novel risk factors and early detection of anti tubercular treatment induced liver injury—Looking beyond American Thoracic Society Guidelines

详细信息    查看全文

• 作者：Muzamil Latief ; Waseem Raja Dar ; ^{drwaseem.mw@gmail.com} ; Najeebullah Sofi ; Imtiyaz Ahmad Dar ; Basharat Kasana ; Moomin Hussain ; Faheem Arshad ; Bashir Ahmad Shah ; Parvaiz Ahmad Koul
• 关键词：Anti-tubercular treatment ; Drug induced liver injury ; Liver function tests
• 刊名：Indian Journal of Tuberculosis
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：64
• 期：1
• 页码：26-32
• 全文大小：747 K
• 卷排序：64

文摘

ATT-induced liver injury is a serious concern in the treatment of tuberculosis. Early detection and interruption of therapy is of utmost importance as is monitoring of liver functions. Besides traditional risk factors, female sex and extrapulmonary tuberculosis are the two main risk factors for the development of DILI. Frequent clinical and biochemical monitoring should be done in high-risk patients during the course of ATT.