The effect of phototherapy on systemic inflammatory process in patients with plaque psoriasis
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- 作者：Aleksandra Batycka-Barana ; aleksandra.batycka-baran@umed.wroc.pl" class="auth_mail" title="E-mail the corresponding author ; Petra Besgenb ; Ronald Wolfb ; Jacek C. Szepietowskia ; Joerg C. Prinzb
- 关键词：Psoriasis ; Phototherapy ; Systemic inflammation ; Cytokines ; Peripheral blood mononuclear cells
- 刊名：Journal of Photochemistry and Photobiology B: Biology
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：161
- 期：Complete
- 页码：396-401
- 全文大小：735 K
文摘
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Systemic effect of phototherapy in patients with psoriasis is not fully elucidated.
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NB-UVB and bath-PUVA affect systemic inflammation in psoriasis.
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Phototherapy regulates the expression of proinflammatory cytokines in PBMCs.
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NB-UVB decreases IL-17A, TNF-α, and IL-6 mRNA levels in PBMCs in psoriatic patients.
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Bath-PUVA decreases TNF-α and IL-6 mRNA levels in PBMCs in psoriatic patients.
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