No difference in paired associative stimulation induced cortical neuroplasticity between patients with mild cognitive impairment and elderly controls
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- 作者：Jacob Lahra ; b ; c ; jacob.lahr@uniklinik-freiburg.de" class="auth_mail" title="E-mail the corresponding author ; Jessica Petera ; b ; c ; Lora Minkovaa ; b ; e ; Eliza Lauera ; Janine Reisc ; Bernhard Heimbachc ; d ; Michael Hü ; lld ; Claus Normannb ; Christoph Nissenb ; Stefan Klö ; ppela ; b ; c ; d
- 关键词：Long-term potentiation (LTP) ; Paired associative stimulation (PAS) ; Mild cognitive impairment (MCI) ; Neural plasticity ; Verbal learning ; LTP-like plasticity ; Transcranial magnetic stimulation (TMS) ; Hippocampal volumetry ; Apolipoprotein E (ApoE)
- 刊名：Clinical Neurophysiology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：127
- 期：2
- 页码：1254-1260
- 全文大小：581 K
文摘
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First report on paired associative stimulation (PAS) in mild cognitive impairment (MCI) patients.
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No difference in PAS induced long-term potentiation (LTP)-like neuroplasticity between MCI patients and elderly controls.
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No correlation between PAS effects and markers of cognitive decline.
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