| ReferencesReferences
Key points
Proton-pump inhibitors remain the most effective treatment for relieving symptoms, healing lesions and preventing recurrences of gastroesophageal reflux (GER). Drugs inhibiting transient relaxation of the lower esophageal sphincter have an unfavorable benefit/risk ratio.
Endoscopic methods developed in recent years have not been shown effective in trials versus sham procedures.
Surgical treatment is effective in GER but causes frequent uncomfortable side effects that are difficult to treat.