New onset postoperative atrial fibrillation predicts long-term cardiovascular events after gastrectomy

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• 作者：Sean P. Nassoiy ; D.O.^a ; Robert H. Blackwell ; M.D.^b ; Anai N. Kothari ; M.D.^a ; ^b ; Stephanie Besser ; M.S.^b ; ^c ; Gopal N. Gupta ; M.D.^b ; ^d ; Paul C. Kuo ; M.D.^a ; ^b ; ^d ; Gerard J. Abood ; M.D.^a ; ^b ; ^d ; ^{gabood@lumc.edu" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Atrial fibrillation ; Gastrectomy ; Myocardial infarction ; Postoperative complications ; Stroke
• 刊名：The American Journal of Surgery
• 出版年：2016
• 出版时间：March 2016
• 年：2016
• 卷：211
• 期：3
• 页码：559-564
• 全文大小：295 K

文摘

Recent evidence suggests transient postoperative atrial fibrillation leads to future cardiovascular events, even in noncardiac surgery. The long-term effects of postoperative atrial fibrillation in gastrectomy patients are unknown.

Methods

The Healthcare Cost and Utilization Project State Inpatient Databases identified patients undergoing gastrectomy for malignancy between 2007 and 2010. Patients were matched by propensity scores based on various factors. Adjusted Kaplan-Meier and Cox proportional hazards models assessed the effect of postoperative atrial fibrillation on cardiovascular events.

Results

A higher incidence of cardiovascular events occurred over the 1st year in patients who developed postoperative atrial fibrillation. Cox proportional hazards regression confirmed an increased risk of cardiovascular events in postoperative atrial fibrillation patients.

Conclusions

Our results demonstrate that patients undergoing gastrectomy for malignancy who develop postoperative atrial fibrillation are at increased risk of cardiovascular events within 1 year. Physicians should be vigilant in assessing postoperative atrial fibrillation, given the increased risk of cardiovascular morbidity.