Double-blind, placebo-controlled study evaluating effects of motor cortex HF-rTMS on nociception in healthy participants.

There was no sign of active rTMS being more anti-nociceptive than sham stimulation.

This was true for both subjective perception and amplitude of evoked potentials and modelled anatomical sources.

Motor cortex HF-rTMS is otherwise known to be effective in decreasing neuropathic pain.

We may hypothesize that it acts upon high-order networks influencing the emotional and cognitive appraisal of chronic pain.