Identification of NUCKS1 as a putative oncogene and immunodiagnostic marker of hepatocellular carcinoma
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- 作者：Jae Youn Cheonga ; d ; jaeyoun620@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Young Bae Kimb ; ybkim@ajou.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Jung Hoon Wooc ; hydepark83@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Dong Kyu Kimd ; dkkim75@cj.net" class="auth_mail" title="E-mail the corresponding author ; Marie Yeod ; marie8346@cj.net" class="auth_mail" title="E-mail the corresponding author ; Song-Ju Yangc ; sjyang0901@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Kap-Seok Yangc ; ksyang@macrogen.com" class="auth_mail" title="E-mail the corresponding author ; Sun Kim Soona ; d ; cocorico99@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Hee Jeong Wange ; wanghj@ajou.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Bong Wan Kime ; drbwkim@ajou.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Jun-Hyung Parkf ; jhpark@insilicogen.com" class="auth_mail" title="E-mail the corresponding author ; Sung Won Choa ; d ; sung_woncho@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Copy number aberration ; Hepatocellular carcinoma ; NUCKS1 ; Diagnostics ; Immunostaining
- 刊名：Gene
- 出版年：2016
- 出版时间：10 June 2016
- 年：2016
- 卷：584
- 期：1
- 页码：47-53
- 全文大小：1168 K
文摘
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Frequent DNA copy number gain on chromosome 1q32.1 was associated with vascular invasion in HCC tissues.
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NUCKS1 was identified as a potential oncogene at chromosomal 1q32.1 in patients with HCC.
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NUCKS1 was over-expressed in the majority of HCCs and might be a valuable immunodiagnostic marker for HCC.