Chronological age and its impact on associative learning proficiency and brain structure in middle adulthood
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- 作者：Vaibhav A. Diwadkara ; vdiwadka@med.wayne.edu" class="auth_mail" title="E-mail the corresponding author ; Marcella Bellanib ; c ; Rizwan Ahmeda ; Nicola Dusib ; c ; Gianluca Rambaldellib ; c ; Cinzia Perlinib ; c ; Veronica Marinellib ; c ; Karthik Ramaseshana ; Mirella Ruggerib ; c ; Paolo Bambillad ; e ; paolo.brambilla1@unimi.it" class="auth_mail" title="E-mail the corresponding author
- 关键词：Aging ; Associative learning ; Brain structure ; Life span changes ; Voxel based morphometry ; Hippocampus
- 刊名：Behavioural Brain Research
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：297
- 期：Complete
- 页码：329-337
- 全文大小：1703 K
文摘
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Neurobiological changes in middle adulthood are relatively understudied.
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Learning proficiency during associative learning appears to decrease through middle adulthood.
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Decreases in gray matter volumes in the hippocampus and the prefrontal cortex.
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Conjoint changes in behavior and brain structures implicate aging related processes.
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Aging in middle adulthood may be more dynamic than previously believed.