Connexins, E-cadherin, Claudin-7 and β-catenin transiently form junctional nexuses during the post-natal mammary gland development
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- 作者：Elham Dianati ; Jé ; ré ; my Poiraud ; Anne Weber-Ouellette ; Isabelle Plante ; isabelle.plante@iaf.inrs.ca" class="auth_mail" title="E-mail the corresponding author
- 关键词：Connexins ; Cadherins ; Claudins ; β‐catenin ; Junctions ; Mammary gland ; Development
- 刊名：Developmental Biology
- 出版年：2016
- 出版时间：1 August 2016
- 年：2016
- 卷：416
- 期：1
- 页码：52-68
- 全文大小：19709 K
文摘
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Gap, tight, adherens junctions' components differentially expressed during the post-natal mammary gland development.
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Junctional proteins are generally localized at the plasma membrane suggesting that they are functional during the development.
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Cx43 constantly interacts with β-catenin, while it's interaction with E-cadherin and Claudin-7 is stage-dependent.
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Cx32 interacts with E-cadherin, β-catenin and Cx26 throughout lactation.
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Cx30 interacts with Cx26 during the last trimester of pregnancy.