Ketamine inhibits human sperm function by Ca2+-related mechanism
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- 作者：Yuanqiao Hea ; b ; Qianxing Zoua ; Bingda Lic ; Houyang Chend ; Xiaohong Due ; Shiqi Wenga ; Tao Luoa ; luotao@ncu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Xuhui Zenga ; zengxuhui@ncu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Acrosome reaction ; [Ca2+]i ; CatSper ; Ketamine ; Sperm motility
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：9 September 2016
- 年：2016
- 卷：478
- 期：1
- 页码：501-506
- 全文大小：934 K
文摘
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Ketamine decreases human sperm motility.
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Ketamine inhibits the progesterone-induced acrosome reaction of human sperm.
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Ketamine lowers human sperm intracellular Ca2+ concentration.
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Ketamine suppresses human sperm CatSper currents.