Modulation of the circadian clock by glucocorticoid receptor isoforms in the H295R cell line

详细信息    查看全文

• 作者：Zsolt Nagy^a ; ^b ; Alexa Marta^a ; Henriett Butz^c ; Istvan Liko^b ; Karoly Racz^a ; ^c ; Attila Patocs^b ; ^d ; ^{patocs.attila@med.semmelweis-univ.hu}
• 关键词：Peripheral clock ; Adrenal gland ; Glucocorticoid receptor ; Clock genes ; Circadian rhythm ; H295R cell line
• 刊名：Steroids
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：116
• 期：Complete
• 页码：20-27
• 全文大小：1007 K
• 卷排序：116

文摘

A functional peripheral clock is present in H295R human adrenocortical cell line. Glucocorticoids influence the expression of multiple clock genes. GRß may modify the regulation of peripheral clock by glucocorticoids through REV-ERBα.