Biodegradable yolk-shell microspheres for ultrasound/MR dual-modality imaging and controlled drug delivery

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• 作者：Peng Yang^a ; ^b ; Xianfu Luo^c ; Sheng Wang^d ; Fang Wang^a ; Chuanbing Tang^b ; Changchun Wang^a ; ^{ccwang@fudan.edu.cn} ; ^{ccwang2012@sina.com}
• 关键词：Yolk-shell structure ; Dual-modality ; Ultrasound imaging ; Magnetic resonance imaging (MRI) ; Controlled drug delivery
• 刊名：Colloids and Surfaces B: Biointerfaces
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：151
• 期：Complete
• 页码：333-343
• 全文大小：4000 K
• 卷排序：151

文摘

Uniform biodegradable yolk-shell Fe3O4@PFH@PMAA-DOX microspheres. Robust dual-modality imaging capability for ultrasound and MR. Control release of DOX under pH, redox and ultrasound stimuli. Degradation of composite microspheres into short hydrophilic polymer chains and iron ions.