Expression and tissue distribution of hepatocyte growth factor (HGF) and its receptor (c-Met) in alpacas (Vicugna pacos) skins associated with white and brown coat colors
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- 作者：Xiuju Yu1 ; Xiaoyan He1 ; Junbing Jiang ; Junping He ; Ruiwen Fan ; Haidong Wang ; Jianjun Geng ; Changsheng Dong ; sxnddcs@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：HGF ; c-Met ; Alpaca ; Coat color ; Skin
- 刊名：Acta Histochemica
- 出版年：2015
- 出版时间：September 2015
- 年：2015
- 卷：117
- 期：7
- 页码：624-628
- 全文大小：1201 K
文摘
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We analyzed the expression patterns and localization of HGF and its receptor in skin of white versus brown alpaca.
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HGF staining showed strongly positive in the dermal papilla and mesenchymal cells of white alpaca skin.
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c-Met staining showed strongly positive in hair matrix and root sheath of brown alpaca skin.
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The protein and transcripts possessed the same expression pattern in white and brown alpaca skin.
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The results offer theoretical basis for exploration on the role of HGF/c-Met signaling in alpaca.