EP 12. TREMOR12: An open-source mobile app for tremor quantification

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• 作者：P. Kubben^a ; ; M. Kuijf^b ; L. Ackermans^a ; A. Leentjens^c ; Y. Temel^a
• 刊名：Clinical Neurophysiology
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：127
• 期：9
• 页码：e178-e180
• 全文大小：691 K

文摘

Evaluating the effect of treatment of tremor is mostly performed with clinical rating scales. Mobile applications facilitate a more rapid, objective and quantitative evaluation of treatment effect. Existing mobile apps do not offer raw data access which limits algorithm development. Our objective is to develop a novel open-source mobile app for tremor quantification.

Methods

TREMOR12 is an open source mobile app that samples acceleration, rotation, rotation speed and gravity, each in 3 axes and time-stamped in a frequency up to 100Hz. The raw measurement data can be exported as a comma-separated value (CSV) file for further analysis in the TREMOR12P data processing module. The app was tested on five healthy volunteers (2 male, 3 female) aged between 22 and 41 years of age.

Results

This proof-of-concept study shows that the TREMOR12 app is able to detect and register tremor characteristics such as acceleration, rotation, rotation speed and gravity in a simple and non-burdensome way. The app is compatible with current regulatory oversight by the European Union (MEDDEV regulations) and the Food and Drug Administration (FDA) guidance on mobile medical applications.

Conclusions

TREMOR12 offers low-cost tremor quantification for research purposes and algorithm development, and may help to improve treatment evaluation.