Thiourea dioxide is eco-friendly, stable and cost-effective with broad applications.

It has been used as coreactant of lucigenin chemiluminescence for the first time.

Dopamine can remarkably inhibit lucigenin/thiourea dioxide chemiluminescence.

Sensitive and selective chemiluminescent detection of dopamine has been achieved.

The detection method also has the advantages of simplicity, rapidity, and low cost.