Musashi 2 contributes to the stemness and chemoresistance of liver cancer stem cells via LIN28A activation
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- 作者：Tian Fanga ; 1 ; Hongwei Lva ; 1 ; Fuquan Wua ; 1 ; Changzheng Wanga ; Ting Lia ; Guishuai Lva ; b ; Liang Tanga ; b ; Linna Guoa ; b ; Shanhua Tanga ; b ; Dan Caoa ; b ; Mengchao Wua ; b ; Wen Yanga ; b ; woodeasy66@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Hongyang Wanga ; b ; c ; hywangk@vip.sina.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Liver cancer ; MSI2 ; LIN28A ; Stemness
- 刊名：Cancer Letters
- 出版年：2017
- 出版时间：1 January 2017
- 年：2017
- 卷：384
- 期：Complete
- 页码：50-59
- 全文大小：3696 K
文摘
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High expression of MSI2 in liver cancer and cancer stem cells.
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MSI2 is well correlated with OV6 expression and poor prognosis in liver cancer.
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To validate the close relation between MSI2 and LIN28A.
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MSI2 promotes stemness and chemoresistance of liver cancer stem cells via LIN28A-dependent manner.