Interaction of homocysteine, glutathione and 8-hydroxy-2′-deoxyguanosine in metabolic syndrome progression

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• 作者：E.G. Butkowski^a ; H.A. Al-Aubaidy^b ; H.F. Jelinek^a ; ^c ; ^{hjelinek@csu.edu.au}
• 关键词：BMI ; Body Mass Index ; CRP ; C - reactive protein ; CVD ; cardiovascular disease ; DBP ; Diastolic blood pressure ; GSH ; Glutathione ; GSSG ; Glutathione disulfide ; HbA1c ; Glycated hemoglobin ; Hcy ; Homocysteine ; HDL ; High density lipoprotein ; IGF-1 ; Insulin-like growth factor-1 ; IL ; Interleukin ; LDL ; Low density lipoprotein ; MCP-1 ; Monocyte Chemotactic Protein-1 ; MDA ; Malondialdehyde ; MetHb ; Methemoglobin ; MetS ; Metabolic syndrome ; 8-OHdG ; 8-hydroxy-2&prime ; -deoxyguanosine ; PGI2 ; Prostaglandin-I2 ; T2DM
• 刊名：Clinical Biochemistry
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：50
• 期：3
• 页码：116-120
• 全文大小：317 K
• 卷排序：50

文摘

Emerging inflammatory and oxidative stress markers correlate with MetS. Hcy is associated with MetS and increases with MetS factors. Hcy did not correlate with GSH or 8-OHdG 8-OHdG was significantly increased in the metabolic syndrome group compared to control.