Partially reduced graphene oxide as highly efficient DNA nanoprobe
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- 作者：Yan-Hong Wanga ; b ; 1 ; Hao-Hua Denga ; b ; 1 ; Yin-Huan Liuc ; Xiao-Qiong Shia ; b ; Ai-Lin Liua ; b ; Hua-Ping Penga ; b ; Guo-Lin Hongd ; 13600885383@139.com" class="auth_mail" title="E-mail the corresponding author ; Wei Chena ; b ; chenandhu@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Partially reduced graphene oxide ; DNA ; Fluorescence ; Quenching ; Sensor
- 刊名：Biosensors and Bioelectronics
- 出版年：2016
- 出版时间：15 June 2016
- 年：2016
- 卷：80
- 期：Complete
- 页码：140-145
- 全文大小：1448 K
文摘
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pRGO is synthesized by incubating GO under alkaline condition at room temperature.
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pRGO possesses higher fluorescence quenching efficiency and faster adsorption rate.
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The binding constant of pRGO is much larger than that of GO toward FAM-ssDNA.
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A universal sensing strategy is proposed for homogeneous detection of DNA.
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Without any amplification process, the limit of detection can reach as low as 50 pM.