High expression of chemokine CCL2 is associated with recurrence after surgery in clear-cell renal cell carcinoma
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- 作者：Yuanfeng Yang ; M.D. ; Ph.D.a ; 1 ; Changwen Zhai ; M.D.b ; 1 ; Yuan Chang ; M.D.a ; 1 ; Lin Zhou ; M.D.a ; Tianming Shi ; M.D.c ; Cheng Tan ; M.D. ; Ph.D.c ; Le Xu ; M.D. ; Ph.D.c ; XL11887@rjh.com.cn" class="auth_mail" title="E-mail the corresponding author ; Jiejie Xu ; Ph.D.d ; jjxufdu@fudan.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Clear-cell renal cell carcinoma ; CCL2 ; Prognostic biomarker ; Recurrence-free survival ; Nomogram
- 刊名：Urologic Oncology: Seminars and Original Investigations
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：34
- 期：5
- 页码：238.e19-238.e26
- 全文大小：1568 K
文摘
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High chemokine CCL2 expression is a predictor of recurrence in ccRCC patients.
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The prognostic value of CCL2 is more pronounced in patients with low-risk disease.
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A nomogram integrating CCL2 and pathologic factors may improve the postoperative management of ccRCC patients.