Serum DHEA-S concentration correlates with clinical symptoms and neurocognitive function in patients with bipolar II disorder: A case-controlled study

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• 作者：Sheng-Yu Lee^a ; ^b ; ^c ; ^{shirleylee.ncku@gmail.com} ; Liang-Jen Wang^d ; Cheng-Ho Chang^a ; Chih-Ching Wu^e ; ^f ; Hsing-Ling Chen^g ; Shih-Hsien Lin^c ; Chin-Liang Chu^a ; Ti Lu^a ; Ru-Band Lu^c ; ^h ; ⁱ
• 关键词：Bipolar II disorder ; Neuroendocrine ; Cognitive function ; DHEA-S ; BACA
• 刊名：Progress in Neuro-Psychopharmacology and Biological Psychiatry
• 出版年：2017
• 出版时间：6 March 2017
• 年：2017
• 卷：74
• 期：Complete
• 页码：31-35
• 全文大小：271 K
• 卷排序：74

文摘

Dysregulation of the neuroendocrine system may be associated with BP-II. BP-II had poorer neuropsychological performance compared to controls. The DHEA-S level was associated with neuropsychological performance. The DHEA-S level was inversely correlated with mania score. DHEA-S level may be a biomarker for manic symptoms and cognitive performance.