One-year outcomes following drug-eluting balloon use for coronary ostial restenosis

详细信息    查看全文

• 作者：Wei-Chieh Lee¹ ; Hsiu-Yu Fang² ; Wen-Jung Chung ; Shu-Kai Hsueh ; Chien-Jen Chen ; Cheng-Hsu Yang ; Hon-Kan Yip ; Chi-Ling Hang ; Chiung-Jen Wu ; ^{leeweichieh1217@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Chih-Yuan Fang
• 关键词：Drug-eluting balloons ; Coronary ostial instent restenosis ; Coronary ostial intervention
• 刊名：IJC Heart & Vasculature
• 出版年：2016
• 出版时间：March 2016
• 年：2016
• 卷：10
• 期：Complete
• 页码：25-28
• 全文大小：259 K

文摘

The management of ostial lesions is one of the challenges of percutaneous coronary intervention (PCI) in recent medicine. Although stent implantation has increased the accuracy of the results and improved long-term outcomes, in-stent restenosis (ISR) occurs more frequency following the treatment of ostial lesions than the treatment of non-ostial lesions. When additional stenting is not desirable, PCI with drug-eluting balloons (DEBs) has emerged as an adjunctive strategy. However, little data regarding the effects of DEBs in ostial ISR lesions are available. Our study aimed to assess the efficacy of the use of DEBs in coronary ostial instent restenotic lesions.

Methods and results

From November of 2011 to May of 2014, 85 patients were diagnosed with coronary ostial ISR in our hospital. A total of 93 coronary ostial ISR lesions were treated with DEBs. More than half of the study patients had comorbidities, including hypertension, diabetes, and hyperlipidemia, 77.6% of the study patients had triple vessel coronary artery disease, and 54.1% of the study patients had left main coronary artery disease. In our study, target lesion revascularization were performed in 19.2% in all groups; 11.5% were in the ostial left anterior descending artery, 29.0% were in the ostial left circumflex artery, and 21.4% were in the ostial right coronary artery. Across all of the groups, 24.4% of the patients experienced major adverse cardiac cerebral events.

Conclusion

Percutaneous coronary intervention with drug-eluting balloons is an alternative strategy for coronary ostial instent restenosis when additional stenting is not desirable.