Biophysical and biological characterization of intraoral multilayer membranes as potential carriers: A new drug delivery system for dentistry

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• 作者：Mariana dos Santos Silva^a ; Natalino Lourenç ; o Neto^a ; Silgia Aparecida da Costa^b ; Sirlene Maria da Costa^b ; Thais Marchini Oliveira^a ; Rodrigo Cardoso de Oliveira^c ; ^{rodrigocardoso@usp.br} ; Maria Aparecida Andrade Moreira Machado^a
• 关键词：Layer-by-layer coatings ; Alginate ; Chitosan ; Cell viability ; Chlorhexidine ; Controlled drug release
• 刊名：Materials Science and Engineering: C
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：71
• 期：Complete
• 页码：498-503
• 全文大小：756 K
• 卷排序：71

文摘

Layer-by-layer deposition of chitosan and alginate was used to control drug release. Therapeutic intraoral membranes were developed to ensure extended drug release. Intraoral membranes are easier to handle and apply on oral soft tissues than other available drug delivery systems.