L-DOPA treatment in MPTP-mouse model of Parkinson’s disease potentiates homocysteine accumulation in substantia nigra
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- 作者：Nivedita Bhattacharjee1 ; Muhammed Khairujjaman Mazumder1 ; Rajib Paul1 ; Amarendranath Choudhury ; Sabanum Choudhury ; Anupom Borah ; anupomborahh@gmail.com" class="auth_mail" title="E-mail the corresponding author ; anupom.borah@aus.ac.in" class="auth_mail" title="E-mail the corresponding author
- 关键词：Hyperhomocysteinemia ; L-DOPA ; Dopaminergic neurons
- 刊名：Neuroscience Letters
- 出版年：2016
- 出版时间：15 August 2016
- 年：2016
- 卷：628
- 期：Complete
- 页码：225-229
- 全文大小：1116 K
文摘
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L-DOPA therapy in Parkinson’s disease causes HHcy.
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Hcy is elevated in nigra of L-DOPA treated parkinsonian mouse.
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HHcy in nigra is a potential threat towards vulnerability of dopamine-rich neurons.
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