Indirect pulsed electrochemical detection of aliphatic carboxylate-containing analytes following high performance anion-exchange chromatography
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- 作者：Loryn R. Keating ; William R. LaCourse ; lacourse@umbc.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Pulsed electrochemical detection ; Indirect detection ; Chromatography ; Anion-exchange ; Gabapentin ; Biotin
- 刊名：Talanta
- 出版年：2016
- 出版时间：1 January 2016
- 年：2016
- 卷：146
- 期：Complete
- 页码：594-602
- 全文大小：981 K
文摘
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The mechanism of indirect pulsed electrochemical detection is explained.
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A single pulsed potential-time waveform can be used for a wide range of analytes.
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Sorbitol as a mobile phase additive produces the best results.
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Detection limits for aliphatic carboxylate-containing compounds are 2–0.05 ppm.
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Over-the-counter formulations are assayed for biotin and proline.