Clinical features and molecular epidemiology of multidrug-resistant Acinetobacter calcoaceticus-A baumannii complex in a regional teaching hospital in Taiwan

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• 作者：Ming-Feng Lin ; Chih-Man Yang ; Chung-Hui Lin ; Mei-Luan Huang ; Chi-Chao Tu ; Ming-Li Liou
• 刊名：American Journal of Infection Control
• 出版年：2009
• 出版时间：November 2009
• 年：2009
• 卷：37
• 期：9
• 页码：e1-e3
• 全文大小：80 K

文摘

We conducted a case-controlled study in a regional teaching hospital in Taiwan to investigate the clinical features and molecular epidemiology of multidrug-resistant Acinetobacter calcoaceticus-A baumannii (MDR Acb) complex. Case patients had higher mortality than controls did. MDR Acb complex acquisition risk factors include longer hospital stays, higher ratio of nasogastric tube and Foley catheter use, and more carbapenem use. All available isolates were divided into 36 subtypes by pulsed-field gel electrophoresis. The proportion of the same subtypes with their appearance within 1 and 2 months was 62.5 % and 87.5 % , respectively. We concluded that many different MDR Acb complex clones could be found in a hospital and that the same clones often spread on a small scale within a short period of time if no outbreaks noted.