Lysozyme was integrated into CS-NPs via ionotropic gelation technology by the interaction between Nlimg="/entities/sbnd" src="/sd/grey_pxl.gif" class="glyphImg imgLazyJSB">H and Olimg="/entities/sbnd" src="/sd/grey_pxl.gif" class="glyphImg imgLazyJSB">H groups.

CS-Lys-NPs showed enhanced antibacterial activity.

The antibacterial action was probably due to the ability of nanoparticles to penetrate the cell membrane or influence metabolism enzyme activities and interfere with bacterial metabolism.