Expression of the insulinoma-associated 1 (insm1) gene in Xenopus laevis tadpole retina and brain

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• 作者：Jennifer L. Bosse^a ; Heithem M. El-Hodiri^a ; ^b ; ^c ; ^{Heithem.El-Hodiri@NationwideChildrens.org" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Xenopus laevis ; insm1 ; Ciliary marginal zone ; Optic tectum ; Dorsal pallium ; Hypothalamus
• 刊名：Gene Expression Patterns
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：22
• 期：1
• 页码：26-29
• 全文大小：1350 K

文摘

The insulinoma-associated 1 (insm1) gene is involved in the differentiation of several neuronal and endoderm derived cell types. insm1 is expressed in the retina and brain of several vertebrates including Xenopus laevis. We report the detailed expression pattern of insm1 in the X. laevis tadpole retina and brain. X. laevis insm1 is expressed in most of the ciliary marginal zone of the mature retina and the optic tectum, dorsal pallium, hypothalamus and preoptic areas of the developing tadpole brain. Overall, insm1 is expressed in regions of the tadpole brain and retina harboring populations of progenitor cells.