Arabidopsis CMT3 activity is positively regulated by AtSIZ1-mediated sumoylation
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- 作者：Do Youn Kima ; Yun Jung Hana ; Sung-Il Kima ; Jong Tae Songb ; Hak Soo Seoa ; c ; seohs@snu.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：AtSIZ1 ; SUMO ; Sumoylation ; CMT3 ; DNA methylation ; DNA methyltransferase
- 刊名：Plant Science
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：239
- 期：Complete
- 页码：209-215
- 全文大小：1170 K
文摘
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AtSIZ1 sumoylates DNA methyltransferase CMT3 through a direct interaction
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Sumoylation enhances the DNA methylation activity of CMT3
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Genome methylation level is down-regulated in siz1-2 and cmt3 mutants than wild type
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Genome methylation level in siz1-2 mutants is lower compared to that in cmt3 mutants
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The methylation of CMT3 target genes is regulated by AtSIZ1-mediated sumoylation of CMT3