Nest building is a novel method for indexing severity of alcohol withdrawal in mice
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- 作者：G.D. Greenberga ; b ; c ; greenbeg@ohsu.edu" class="auth_mail" title="E-mail the corresponding author ; giangreenberg@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; L.C. Huanga ; b ; c ; S.E. Spencea ; b ; c ; J.P. Schlumbohma ; b ; c ; P. Mettena ; b ; c ; A.R. Ozburna ; b ; c ; J.C. Crabbea ; b ; c
- 关键词：EtOH ; ethanol ; HIC ; handling-induced convulsion ; BEC ; blood ethanol concentration ; i.p. ; intraperitoneally ; h ; hours ; PDT ; Pacific Daylight Time
- 刊名：Behavioural Brain Research
- 出版年：2016
- 出版时间：1 April 2016
- 年：2016
- 卷：302
- 期：Complete
- 页码：182-190
- 全文大小：1436 K
文摘
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Chronic ethanol vapor inhalation dose-dependently suppressed nest building for up to 32 h after withdrawal.
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Withdrawal from an acute, high dose (4 g/kg) of ethanol reduced nest building for up to 32 h.
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Body temperature predicted nest building in naïve HS/Npt mice but not in the same mice following ethanol vapor chamber exposure.