Toxicity assessment of sodium fluoride in Drosophila melanogaster after chronic sub-lethal exposure
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- 作者：Moumita Duttaa ; Prem Rajakb ; Salma Khatuna ; Sumedha Roya ; roysumedha@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Drosophila melanogaster ; Fluoride ; Hsp 70 ; Detoxifying enzymes ; Comet assay ; Sodium fluoride
- 刊名：Chemosphere
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：166
- 期：Complete
- 页码：255-266
- 全文大小：1929 K
文摘
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Chronic sub-lethal NaF exposure increases body F− conc. in D. melanogaster.
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Elevated HSP70, DNA and tissue damage confirm stress at selected NaF concentration.
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NaF treatment alters the activities of SOD, CAT, Cyp450, GST and AChE enzymes.
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Increased LPO activity confirms oxidative stress due to NaF exposure.
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Selected NaF concentrations can induce paradoxical toxic responses in Drosophila.