Conditioned medium of olfactory ensheathing cells promotes the functional recovery and axonal regeneration after contusive spinal cord injury
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- 作者：Mengchao Gua ; Zhengchao Gaoa ; Xiaohui Lib ; Lei Guoa ; Teng Lua ; Yuhuan Lia ; Xijing Hea ; xijing_h@vip.tom.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Olfactory ensheathing cells (OECs) ; Conditioned medium ; Spinal cord injury (SCI) ; Axonal regeneration ; Diffusion tensor imaging (DTI)
- 刊名：Brain Research
- 出版年：2017
- 出版时间：1 January 2017
- 年：2017
- 卷：1654
- 期：part_PA
- 页码：43-54
- 全文大小：3331 K
文摘
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We present a novel cell-free OEC based cell therapy to treat contusive SCI.
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OEC-M treatment promotes functional recovery and axonal regeneration after SCI.
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DTI is applied as a novel method to assess the axonal regeneration of spinal cord.
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Conventional MRI and DTT are applied to visualize the repair process after SCI.
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NF200 staining confirms the axonal regeneration around the injury epicenter.
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