An intergated serum and urinary metabonomic research based on UPLC-MS and therapeutic effects of Gushudan on prednisolone-induced osteoporosis rats
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- 作者：Yue Huang ; Yunhai Bo ; Xiao Wu ; Qiuyi Wang ; Feng Qin ; Longshan Zhao ; Zhili Xiong ; bearry200@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Gushudan ; Osteoporosis ; UPLC-MS ; Metabonomics ; Principle component analysis
- 刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences
- 出版年：2016
- 出版时间：1 August 2016
- 年：2016
- 卷：1027
- 期：Complete
- 页码：119-130
- 全文大小：1944 K
文摘
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An intergated serum and urinary metabonomic to study osteoporosis has been proposed.
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The mechanism of Gushudan relies on regulating multiple metabolic pathways.
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The potential biomarkers associated with osteoporosis have been identified.